New UPLC-MS/MS bioanalytical method for quantification of Glycopyrronium and Indacaterol
We are glad to announce that a new method has been successfully developed and validated for determination of Glycopyrronium and Indacaterol in human plasma by LC/MS/MS with a calibration range of 1-200 pg/mL and 2-250 pg/mL, respectively.
Since both analytes can be quantified in a single run, it allows for reduced volumes of blood required, a faster turnaround time for sample analysis and significant cost advantages.
The method involves a solid-phase extraction procedure. Glycopyrronium, Indacaterol and internal standards are measured by reversed phase ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UPLC-MS/MS).
The development of this assay adds to the long experience of Anapharm with high sensitivity methods for inhaled drugs including Tiotropium, Fluticasone, Salmeterol and Formoterol.
Anapharm Bioanalytics Brazilian ANVISA Certificate Renewal
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Challenges in the Detection of Metabolic Biomarkers Using a Multi Plex Assay
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